Fig. 3: Selected reaction monitoring chromatograms of SARS-CoV-2-positive clinical respiratory tract specimen showing targeted peptides. | Nature Communications

Fig. 3: Selected reaction monitoring chromatograms of SARS-CoV-2-positive clinical respiratory tract specimen showing targeted peptides.

From: Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts

Fig. 3

a Qualitative (Tier 3) assay; b Quantitative (Tier 1) assay. The first three residues of each peptide are used to label peptide peaks: DGI (DGIIWVATEGALNTPK) and IGM (IGMEVTPSGTWLTYTGAIK) from nucleoprotein; HSG (HSGFEDELSEVLENQSSQAELK) from 15N-labeled surrogate standard chromogranin A (in Tier 3) and SYE (SYELPDGQVITIGNER) from human beta actin (in Tier 1).

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