Fig. 9: In vivo photothermal evaluation of H4-PEG-PT against osteosarcoma.
From: Upconversion NIR-II fluorophores for mitochondria-targeted cancer imaging and photothermal therapy
a PBS and b H4-PEG-PT solution injected to tumor bearing mice under 808 nm laser irradiation (1.5 W cm−2). c Representative photographs of mice after different treatments: H4-PEG-PT only, PBS under 808 nm laser irradiation, and H4-PEG-PT exposed to 808 nm irradiation, respectively. Red dashed arrows indicated tumor. d Photographs of tumor tissue obtained in different groups after 14 d treatment, respectively. e Tumor volumes and f body weight of different groups of 143B tumor-bearing mice after treatment (n = 4 biologically independent mice). Data are presented as mean values ± SD (e, f). Statistical significance was calculated with two-tailed Student’s t test (e).
