Fig. 1: KIFC1 predicts human tumor recurrence. | Nature Communications

Fig. 1: KIFC1 predicts human tumor recurrence.

From: The ATM and ATR kinases regulate centrosome clustering and tumor recurrence by targeting KIFC1 phosphorylation

Fig. 1

The correlation of KIFC1 protein expression and tumor recurrence or poor prognosis in breast cancer (n = 140, a–d) or colorectal cancer (n = 83, e–h) tissue chips. a, b, e, f Data are representative of the KIFC1 stained tumor or adjacent non-tumor tissues (a, e) (scale bar, 50 μm) with quantitative analysis of clinical samples of tumor recurrence or non-recurrence (b, f). KIFC1 expression was classified as high, medium, or low according to the staining signals. Two-tailed t test p values: p = <0.00001 (b). c, d, g, h The tables show the relative levels of KIFC1 expression with patient age or gender in breast cancers (c) or colorectal cancers (g). Kaplan–Meier plot of overall survival of patients with breast cancer (d) or colorectal cancer (h) stratified by the KIFC1 expression level. A log-rank test was used for statistical analysis. All data presented in this figure show mean values ± SD. Statistical significance was determined by Two-tailed t test. Source data are provided as a Source Data file.

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