Fig. 3: Antigenic similarity of rVSV-ΔG-spike and SARS-CoV-2.
From: A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge
a Immunofluorescent images of Vero E6 cells infected with either WT-VSV (left panel), rVSV-ΔG-spike (middle panel), or SARS-CoV-2, stained with COVID-19 human convalescent serum. Representative images of five experiments are presented. Scale bars: 50 µm. b Correlation analysis of neutralization of rVSV-∆G-spike and SARS-CoV-2 by a panel of sera from COVID-19 convalescent patients. For each serum sample (n = 12), NT50 values were determined for neutralization of rVSV-∆G-spike or SARS-CoV-2. The NT50 values were plotted to determine the correlation between the neutralization assays. Spearman’s correlation r and p values are indicated. Source data are provided as a Source Data file.
