Fig. 6: In vivo contrast enhancement of OCT images of CNV in rabbits. | Nature Communications

Fig. 6: In vivo contrast enhancement of OCT images of CNV in rabbits.

From: Chain-like gold nanoparticle clusters for multimodal photoacoustic microscopy and optical coherence tomography enhanced molecular imaging

Fig. 6

a, b 3D OCT images before and after the injection of CGNP clusters-RGD. ai–aiii, bi–biii B-scan OCT images of one vertical slice (white dotted lines) through the retina. The distribution of CGNP clusters-RGD were clearly observed on 3D OCT image after injection (white dotted circle). c Cross-sectional B-scan OCT images obtained at different time points after the administration of CGNP clusters-RGD (2 h, 24 h, 48 h, 73 h, days 4, 5, 7, 9, 11, and 14). White arrows show the position of CNV. Rabbit injected with CGNP clusters-RGD show significant enhancement of OCT signals. d The error bars in d represent the standard deviation of the mean OCT intensities (N = 3). Source data are provided as a Source Data file.

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