Table 1 Distribution of cases and controls available for the vitamin D and cancer risk MR analysis using summary statistics from various sources.
Cancers | Number of controls | Number of cases | Source (PMID) | Studies |
|---|---|---|---|---|
Barrett’s oesophagus (BE) and oesophageal cancer | 17,159 | 10,279 | 27527254 | BEACON + BONN + OXFORD (BE only) + CAMBRIDGE |
Barrett’s oesophagus (BE) | 17,159 | 6167 | 27527254 | |
Oesophageal cancer | 17,159 | 4112 | 27527254 | |
Breast cancer | 105,974 | 122,977 | 29059683 | BCAC |
ER + breast cancer | 105,974 | 69,501 | 29059683 | |
ER- breast cancer | 105,974 | 21,468 | 29059683 | |
Endometrial cancer | 108,979 | 12,906 | 30093612 | ECAC |
EC endometrial cancer | 46,126 | 8758 | 30093612 | |
NEEC endometrial cancer | 35,447 | 1230 | 30093612 | |
Lung cancer | 15,861 | 11,348 | 24880342 | ILCCO (MR-Base) |
Lung adenocarcinoma | 14,894 | 3442 | 24880342 | |
Squamous cell lung cancer | 15,038 | 3275 | 24880342 | |
Melanoma skin cancer | 26,409 | 15,990 | 26237428 | GenoMEL |
Keratinocyte cancers | QSKIN, 23andMe | |||
Squamous cell carcinoma | 285,355 | 7400 | 31174203 | |
Basal cell carcinoma | 279,049 | 14,940 | 31174203 | |
Neuroblastoma | 3254 | 1627 | 23222812 | MR-Base |
Ovarian cancer | 40,941 | 25,509 | 28346442 | OCAC |
Clear cell | 40,941 | 1366 | 28346442 | |
Endometrioid | 40,941 | 2810 | 28346442 | |
High-grade serous | 40,941 | 13,037 | 28346442 | |
Low-grade serous | 40,941 | 1012 | 28346442 | |
Mucinous | 40,941 | 1417 | 28346442 | |
Pancreatic cancer | 1939 | 1896 | 19648918 | PanScan (MR-Base) |
Prostate cancer | 61,106 | 79,148 | 29892016 | PRACTICAL |
