Fig. 4: Cu2+ sequestration and EECR in continuous flow.
From: Enantioselective extraction of unprotected amino acids coupled with racemization

a When (R)-1 was used as the extractant, a striking color change indicating the transfer of Cu(II) from the aqueous to the organic layer was observed. b When (R)-5 was used as the extractant, the color did not change over five EECR cycles. c Schematic design of continuous reaction system (CRS) that carries out EECR and hydrolysis reactions repeatedly. d Photographs of CRS in operation on the lab bench. The apparatus was manufactured to accommodate a total solution volume of 100 mL.