Table 1 LOD and SNR enhancement of ss-SERS.

From: Spread spectrum SERS allows label-free detection of attomolar neurotransmitters

Neurotransmitters

Dopamine @1402 cm−1

Serotonin @927 cm−1

Acetylcholine@1150 cm−1

GABA @1260 cm−1

Glutamate@1114 cm−1

LOD with ss-SERS

1.9 aM

3.0 aM

1.0 aM

99 aM

39 aM

Measured SNR EF (SNRss-SERS/SNRSERS) @ 1 mM

1.9 × 103

1.3 × 103

1.5 × 103

0.5 × 103

0.8 × 103

Reported LOD with SERS27,31

600 nM

100 nM

4.0 μM

50 μM

600 nM