Fig. 9: GOx-DCL by HPLC.
From: Biomimetic selenocystine based dynamic combinatorial chemistry for thiol-disulfide exchange
Conditions: building blocks 1–2 (95 μM each) and 3–4 (190 μM each), Secox (5% mol, 28.5 μM), GOx (57 μM), Tris buffer (20 mM, pH 7.8), T = 6 °C, 2.5% (v/v) DMSO. Yellow circle (S–S), black hexagon (benzene ring). a DCL chromatograms after 24 h (i) in absence, blank (ii) and presence of GOx, templated. b GOx templated effect relative peak area (RPA) and normalized change of RPA in the presence and absence of Secox (Supplementary Tables 11 and 12). DCC experiments were carried out in triplicate. Mean ± SD.
