Table 1 Gene set enriched in human AML sample after chemotherapy.

From: Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML

Gene Set name

FDR q-value

HALLMARK_UV_RESPONSE_DN

1.31Eāˆ’06

HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

7.38Eāˆ’05

HALLMARK_IL2_STAT5_SIGNALING

7.38Eāˆ’05

HALLMARK_COAGULATION

7.93Eāˆ’05

HALLMARK_PROTEIN_SECRETION

1.61Eāˆ’04

HALLMARK_ANDROGEN_RESPONSE

2.56Eāˆ’03

HALLMARK_APICAL_JUNCTION

2.56Eāˆ’03

HALLMARK_COMPLEMENT

2.56Eāˆ’03

HALLMARK_KRAS_SIGNALING_UP

2.56Eāˆ’03

HALLMARK_MTORC1_SIGNALING

2.56Eāˆ’03

HALLMARK_APOPTOSIS

8.77Eāˆ’03

HALLMARK_MITOTIC_SPINDLE

1.62Eāˆ’02

HALLMARK_XENOBIOTIC_METABOLISM

1.62Eāˆ’02

HALLMARK_TGF_BETA_SIGNALING

4.78Eāˆ’02

  1. Gene set overlap analysis of the gene set highly expressed in human AML samples described by Hackl et al.32 with Hallmarks gene sets from MsigDB was performed.
  2. EntriesĀ related to mTORC1 signal are highlighted in bold.
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