Table 2 Gene set enriched in human drug resistant AML after chemotherapy.

From: Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML

Gene Set name

FDR q-value

HALLMARK_ALLOGRAFT_REJECTION

3.43Eāˆ’16

HALLMARK_MTORC1_SIGNALING

1.18Eāˆ’11

HALLMARK_TNFA_SIGNALING_VIA_NFKB

1.18Eāˆ’11

HALLMARK_IL2_STAT5_SIGNALING

1.49Eāˆ’09

HALLMARK_INFLAMMATORY_RESPONSE

1.49Eāˆ’09

HALLMARK_IL6_JAK_STAT3_SIGNALING

1.19Eāˆ’08

HALLMARK_COMPLEMENT

1.19Eāˆ’08

HALLMARK_KRAS_SIGNALING_UP

1.19Eāˆ’08

HALLMARK_INTERFERON_GAMMA_RESPONSE

1.33Eāˆ’06

HALLMARK_ADIPOGENESIS

1.05Eāˆ’05

  1. Gene-set overlap analysis of the gene set highly expressed in drug resistant human AML samples described by Saito et al.31 with Hallmarks gene sets from MsigDB was performed.
  2. Entries related to mTORC1 signal are highlighted in bold.
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