Fig. 2: Mutational events in smoldering myeloma in comparison to myeloma.

a The most frequently mutated genes and their distribution across the most common molecular subgroups. b The distribution of somatic abnormalities per sample and risk group. c Frequency of biallelic and monoallelic events per driver locus in SMM and MM showing fewer biallelic drivers in SMM. *Significantly different at p < 0.05 level, two-sided Fisher’s test.