Fig. 7: Mutational signatures. | Nature Communications

Fig. 7: Mutational signatures.

From: The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma

Fig. 7

Mutational signatures. a The mutational signature composition does not differ between patients that progress more or less than 2 years after the sample was taken and those who do not progress. Boxplots representing second quartile, median, third quartile, whiskers representing first, and fourth quartile. All data points including outliers are represented. b The contribution of mutational signatures did not vary substantially according to clonality. c The CCF of genes increased overtime suggesting they may be drivers. HRD hyperdiploid, nHRD non-hyperdiploid, SBS single base substitution, CCF cancer clonal fraction. Error bands = 95% CI.

Back to article page