Fig. 5: Infra-slow to high-gamma correlates of sleep and behavioral states. | Nature Communications

Fig. 5: Infra-slow to high-gamma correlates of sleep and behavioral states.

From: Graphene active sensor arrays for long-term and wireless mapping of wide frequency band epicortical brain activity

Fig. 5

a 3D trajectories of the head position of the rat. The inset shows a scheme of the position of the Mocap. b The spectrogram and raw LFP signal of an illustrative channel is displayed for distinct brain states (top); slow-wave (SW), high-voltage spindles (HVS) and Theta. Movement speed is displayed along with classification of motor state (middle) and brain states (bottom). c Top: percentage of time in the active vs. inactive state (interruptions to replace the battery not included). Bottom: percentage of time the rat was in each main brain state. d Average 0.015–4 Hz spectrogram for one DC channel triggered on REM episode onsets (n = 44). e Median PSD across SWS-REM transition episodes (n = 44) for 30 s periods pre and post REM onset. Shaded area marks frequency bins with significant difference (p < 0.05, permutation test). f Color-coded strength of modulation of LFP power across slow frequency range (y-axis) for one channel by the phase of ISA across 0.05–0.2 Hz range derived from one DC channel (see panel g) during REM sleep (left) and SWS (right) states. Gray color indicates nonsignificant modulation. Insets show circular plot of LFP power in theta/spindle band as a function of ISA phase. g Color-coded topographic maps of ISA phase modulation of LFP power in theta band during REM (left) and spindle band during SWS (right). ISA phase derived from DC channel marked with a red square. h Color-coded strength of modulation of LFP power across gamma frequency range (y-axis) for one channel by the phase of ISA across 0.05–0.2 Hz range derived from one DC channel (left) and by the phase of LFP in the slow frequency range rhythm (right) during REM. Inset, circular plot of LFP gamma power with respect to respective (ISA or theta) phase. i Average spectrogram for high-frequency range of LFP on posterior channel triggered on rear onset (n = 162). j Head elevation (bottom) and high gamma power (top, same channel as in i) color-coded and centered on rearing onset shown for all events sorted by duration of rear event.

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