Fig. 2: Atg3 NTs have conserved membrane curvature sensitivity. | Nature Communications

Fig. 2: Atg3 NTs have conserved membrane curvature sensitivity.

From: An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy

Fig. 2

a, b Helical wheel plots for hAtg3 and yAtg3 amphipathic helix. Residues are colored as in Fig. 1a. c, d CD spectra of hAtg3 NT and yAtg3 NT, respectively, in the absence and presence of 10% DOPG, 90% POPC sonicated, and 50 nm extruded liposomes. Average sizes for sonicated and 50 nm extruded liposomes, measured by dynamic light scattering, are 32 and 56 nm, respectively.

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