Fig. 4: Prevalence of most representative single nucleotide polymorphisms (SNPs) in SARS-CoV-2 genomes isolated in Lombardy according to geographical locations and their intra-patient prevalence. | Nature Communications

Fig. 4: Prevalence of most representative single nucleotide polymorphisms (SNPs) in SARS-CoV-2 genomes isolated in Lombardy according to geographical locations and their intra-patient prevalence.

From: Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy

Fig. 4

a Frequency of single nucleotide polymorphisms (with respect to the Wuhan reference genome NC_045512.2) among SARS-CoV-2 sequences according to different geographical location. Italian sequences include the 6 and 8 sequences from North and Central Italy present in Gisaid at April 10. b Intra-patient prevalence of most representative SNPs in North Italian SARS-CoV-2 sequences according to sample date. Box and whiskers plots indicate the median and interquartile range of intrapatient prevalence. SNP: single nucleotide polymorphism; syn: synonymous; non-syn: non-synonymous; nsp15: non-structural protein 15; S: spike; M: matrix; N: nucleocapsid; RdRp: RNA-dependent RNA polymerase.

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