Fig. 3: Extended TNF–TNFR1 chain.

Four copies of trimeric mTNF (green ribbons) linked by hTNFR1 dimers (pink surface rendered) as present in the crystal lattice (PDB: 7KP8 [https://www.rcsb.org/structure/unreleased/7KP8]). Membrane proximal ends of each receptor are highlighted in red.