Fig. 6: Examples of de novo proteins in sense–antisense gene pairs.
From: Uncovering de novo gene birth in yeast using deep transcriptomics

The thick arrows represent coding sequences whereas the lines represent the rest of the transcript as defined by our pipeline. ORF denotes open reading frames that are not annotated but which are translated proteins according to the analysis of ribosome profiling data. For convenience the youngest protein (in bold) is always shown in the upper part of the diagram, regardless of whether it is in the positive or negative strand. This representation focuses on the conservation at the level of the transcript. The conservation of the protein may be more restricted as is the case of MDF1, which is only found in S. cerevisiae.