Fig. 1: Serological profile of 26 Israeli actively infected tuberculosis patients. | Nature Communications

Fig. 1: Serological profile of 26 Israeli actively infected tuberculosis patients.

From: Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis

Fig. 1

Serum responses by ELISA against a Mtb-H37Rv lysate, b Mtb-CDC1551 lysate, c Mtb-H37Ra lysate and cell-wall fraction, and recombinant proteins d PstS1, e antigen 85b (Ag85b), f CFP10 + ESAT6 complex, g Hbha, and h Malate Synthase. Every symbol represents a single patient, with the legend given on the right side of the figure. ATB patients are in red symbols and negative community controls are in green symbols. A heat map summarizing ELISA signals against the different antigens and lysates is shown in (i). Donor P.4 is marked with a black arrow. All error bars are represented as mean ± SD. All statistics were derived for n = 26 ATB patients versus n = 20 negative community controls, except for (a, b) n = 19 negative community controls. Significance was determined using a two-tailed unpaired Welch’s t test. ns no significance. Data are representative of at least two independent experiments.

Back to article page