Fig. 5: Structure modeling of the binding of PstS1 to the PstA–B–C phosphate transporter complex. | Nature Communications

Fig. 5: Structure modeling of the binding of PstS1 to the PstA–B–C phosphate transporter complex.

From: Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis

Fig. 5

a Structural superimposition of the Fab–PstS1 complexes with MetQ of the MetNIQ ABC transporter complex (in gold) (PDB code: 6CVL) suggested a possible binding mode of PstS1 to the PstA–B–C phosphate transporter complex. The bound antibodies show no blockage to the assembly of the PstA–B–C–S complex. b Sequence alignments showing that the MetNIQ complex components share significant sequence similarities to these of the PstA–B–C phosphate transporter complex of Mtb.

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