Fig. 2: Heterogenous tuning to pitch, roll, and azimuthal head velocity.
From: Mouse entorhinal cortex encodes a diverse repertoire of self-motion signals
a Model-derived tuning curves (mean ± sem of 10 models) for cells significantly encoding pitch (Supplementary Figs 5–8). The stability (“S”) and tuning curve class (1° = linear, etc.) are indicated at the top. aii Bottom: Spiking from a pitch-encoding cell. Gray trace, pitch position. Black dots, spikes. Top: The associated tuning curve. aiii Summary of tuning curve classes. Bar color denotes downward/upward preference. aiv Preferred position for cells non-linearly encoding pitch. av Stability of tuning to pitch. Boxplots: stability did not significantly differ between classes (median [1st–3rd quartile]; 1° = 0.77 [0.52–0.84], n = 17; 2° = 0.70 [0.32–0.80], n = 16; >2° = 0.41 [0.10–0.66], n = 11; Χ2 = 4.21, P = 0.12, df = 2; Kruskal–Wallis test). bi Tuning curves for cells significantly encoding roll. bii Spiking from a roll-encoding cell. biii Summary of tuning curve classes. Bar color denotes directional preference. biv Preferred position for cells non-linearly encoding roll. bv Stability of tuning to roll. Boxplots: stability did not significantly differ between classes (median [1st–3rd quartile]; 1° = 0.68 [0.46–0.91], n = 10; 2° = 0.54 [0.19–0.76], n = 28; >2° = 0.37 [0.26–0.71], n = 14; Χ2 = 2.7, P = 0.26, df = 2; Kruskal–Wallis test). ci Tuning curves for cells significantly encoding azimuthal head velocity (n = 67 cells from two datasets; Methods). Las, linear asymmetric; NLas, nonlinear-asymmetric; NLs, nonlinear-symmetric; Pos, positive; Neg, negative. cii Spiking from an azimuthal head velocity-encoding cell. ciii Summary of tuning curve classes. Bar color indicates directional preference. civ Cells' sensitivity in the contraversive versus ipsiversive rotational ranges. Units = spikes/s/°/s. cv Stability of tuning to azimuthal head velocity. Boxplots, stability did not significantly differ between classes (median [1st–3rd quartile]; Las = 0.78 [0.44–0.99], n = 10; NLas = 0.92 [0.87–0.96], n = 28; NLs = 0.88 [0.71–0.96], n = 26; Χ2 = 0.73, P = 0.70, df = 2; Kruskal–Wallis test). Boxplots; box, interquartile range; solid line, median; whiskers, range; outliers plotted separately. NS; not significant.
