Fig. 2: Binding mode of JNJ-31020028 in Y2R. | Nature Communications

Fig. 2: Binding mode of JNJ-31020028 in Y2R.

From: Structural basis for ligand recognition of the neuropeptide Y Y2 receptor

Fig. 2

a Ligand-binding pocket for JNJ-31020028. Y2R is shown in gray cartoon representation. The Y2R residues (carbon in cyan) that form interactions with JNJ-31020028 are shown as sticks. JNJ-31020028 (carbon in yellow) is shown as sticks and hydrogen bonds are shown as red dashed lines. b Schematic representation of interactions between Y2R and JNJ-31020028 analyzed using LigPlot+ program47. The Y2R residues engaged in hydrogen bonds are shown as cyan sticks. Hydrogen bonds are shown as red dashed lines.

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