Fig. 4: Risk allele frequency and standardized integrated haplotype scores (iHS) across different populations for the Asian-specific variant at TNFRSF13B locus. | Nature Communications

Fig. 4: Risk allele frequency and standardized integrated haplotype scores (iHS) across different populations for the Asian-specific variant at TNFRSF13B locus.

From: Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups

Fig. 4

a Frequency for the risk allele rs34562254-A across populations. b Standardized iHS for the variants across different continental populations (EAS: East Asians; AFR: Africans; EUR: Europeans). The risk allele rs34562254-A is a derived allele, and negative iHS value indicates that the haplotypes carrying the derived allele are longer than the haplotypes carrying the ancestral allele. The frequency and iHS were calculated using data from the 1000 Genomes Project.

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