Fig. 2: Vertex-wise GAMM effects.

a Significance map for age-related changes in asymmetry in the LCBC discovery sample (2577 observations; Age × Hemisphere GAMM interaction; one-sided F-test). b Mean thickness asymmetry for the discovery sample, irrespective of age (main effect of Hemisphere; two-sided test). Only regions showing significant asymmetry are shown. Warm and cold colors indicate leftward and rightward thickness asymmetry (mm), respectively. Maps in (a, b) are corrected for multiple comparisons using false discovery rate (FDR)35 at p(FDR) < 0.001. Lat lateral, Med medial, Inf inferior.