Fig. 2: SARS-CoV-2 live-virus neutralisation antibody titre in serum and correlation with IgG and IgM responses. | Nature Communications

Fig. 2: SARS-CoV-2 live-virus neutralisation antibody titre in serum and correlation with IgG and IgM responses.

From: Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection

Fig. 2

a The percentages of patients with serum samples that were positive for neutralising antibody (NAb) and log10-transformed geometric mean titer (GMT). Error bars represent 95% confidence interval. Each circle represents the titer for a serum sample. b Individual NAb titer in serum samples collected from patients, and the samples from the same patients are connected by the lines. c Correlations between SARS-CoV-2-specific NAb titer and anti- nucleoprotein (N), -spike (S), and -receptor-binding domain (RBD) IgG levels and anti-RBD IgM, and the correlation between anti-S IgG and anti-S IgG. Statistical comparisons were performed using the two-sided nonparametric Spearman correlation. p value and spearman’s rho are presented. p = 4.79E-16, 9.93E-19, 8.46E-16, and 2.76E-18 for anti-N IgG, anti-RBD IgM, anti-S IgG, and anti-RBD IgG with NAb correlation, respectively, and p = 1.78E-43 for anti-S IgG with anti-RBD IgG correlation. Source data included as a Source Data File.

Back to article page