Fig. 7: Characterization of tissue-specific antigen expression by human TECs. | Nature Communications

Fig. 7: Characterization of tissue-specific antigen expression by human TECs.

From: Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla

Fig. 7

a UMAP visualization of the average expression of tissue-specific antigens (TSA score) in medullary epithelial cells. b UMAP visualization of the expression of genes that positively correlate with a high TSA score in AIRE+ or corneocyte-like mTECs. c UMAP plots showing the expression of antigens eliciting autoantibodies in APS-1 patients. d Feature plots of antigens eliciting autoantibodies in type 1 diabetes and myasthenia gravis patients.

Back to article page