Fig. 4: Comparison of allele frequency and effect size for known loci.

a The effect size (Beta) for loci showing replication after correction for multiple testing in QGP (blue bars) compared to Biobank Japan project (BBJ7, orange bars). b Correlation of effect size for replicated loci between QGP and BBJ. c Correlation of allele frequency for replicated loci between QGP and BBJ (r = 0.80), QGP and European (EUR; r = 0.94), or QGP and African (AFR; r = 0.85) populations. Dotted lines represent lines of best fit from regression analysis.