Fig. 2: Clinical trajectories of PEP seekers diagnosed with HIV (n = 22).

Nine individuals presented clinical signs compatible with primary HIV infection (i.e., acute or recent infection). PEP failure was possible in 6 cases: the start of the infection window occurred within 3 months of PEP consultation (cases number 5, 9, 11, 18 and 22), or HIV was diagnosed at 3 months (case number 1). In case number 22, the estimated time of infection and medical history were compatible with transmission 9 days before PEP consultation (part a). PEP: post-exposure prophylaxis.