Fig. 2: Development of reaction conditions.
Conditions: 1a (0.1 mmol), [Rh(cod)Cl]2 (1 mol%), ligand (3 mol%), in 1.0 mL solvent under Argon atmosphere. The yield was determined by 1H NMR using CH2Br2 as internal standard, yield in brackets is isolated yield. The ee values were determined by chiral HPLC.
