Fig. 1: Postn is highly expressed in postnatal tendon development and endogenous tendon injury repair. | Nature Communications

Fig. 1: Postn is highly expressed in postnatal tendon development and endogenous tendon injury repair.

From: Functional regeneration and repair of tendons using biomimetic scaffolds loaded with recombinant periostin

Fig. 1

a Heatmap of the 32 differentially expressed gene profiles between neonatal and 6–8-week-old tendons (n = 3 rats per group). b Immunohistochemistry of Postn expression in the P 1d and P 6w Achilles tendons (n = 3 rats per group). c, d RT-qPCR of Postn, Scx, and Mkx expression (c, n = 3 independent experiments, by two-tailed Student’s t test: ***P < 0.001, **P < 0.01) and Western blotting of Postn, Tnmd, Mkx at P 1d and P 6w (d). e Immunofluorescence staining of Postn, Sox2, and Oct4 in the rat Achilles tendon between P 1d and P 6w groups (n = 5 rats per group). f Immunofluorescence staining of Postn, Sox2, and Oct4 in normal and injured Achilles tendons at 1 week postoperatively (n = 5 rats per group). Data are presented as mean ± SD. Exact P values were given in the Source Data file.

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