Table 2 Presenting vital signs and laboratory data in the propensity-matched cohort of patients hospitalized with COVID-19.

From: Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19

 

Statins use

(n = 648)

No statins use

(n = 648)

p value

Presenting vital signs

  Temperature

99.0 (98.2–100.1)

98.8 (98.2–100.0)

0.21

    Fever (temperature > 100.4 °F)

139 (21.4%)

129 (19.9%)

0.54

  Respiratory rate

18.0 (18.0–20.0)

19.0 (18.0–22.0)

0.19

    Tachypnea (RR > 21)

143 (22.1%)

186 (28.7%)

<0.01

  Oxygen saturation

94.0 (90.0–97.0)

94.0 (89.0–96.0)

0.06

    Hypoxia (Oxygen saturation <92%)

186 (28.7%)

204 (31.5%)

0.30

  Systolic blood pressure

123.0 (109.0–139.0)

124.0 (110.0 – 141.0)

0.38

  Diastolic blood pressure

72.0 (64.8–81.0)

73.0 (65.0–81.0)

0.08

    Hypotension (SBP < 90 mmHg)

25 (3.9%)

15 (2.3%)

0.15

  Heart rate

96.0 (86.0–109.3)

98.0 (86.0–110.3)

0.47

    Tachycardia (HR > 100)

270 (41.7%)

287 (44.3%)

0.37

Presenting laboratory values

  White blood cell count (103/µL)

7.6 (5.5–10.3)

8.1 (5.8–11.6)

<0.01

  Platelet count (103/µL)

235.0 (159.0–329.0)

224.0 (149.0–314.0)

0.43

  Creatinine (mg/dL)

1.8 (1.1–3.3)

1.9 (1.1–3.8)

0.19

  AST (U/L)

81.0 (44.8–126.3)

84.0 (45.5–142.5)

0.32

  ALT (U/L)

62.5 (33.3–95.8)

60.5 (33.3–107.3)

0.43

  Albumin (g/dL)

3.6 (2.8–4.4)

3.6 (2.7–4.4)

0.93

  Lactate (mmol/L)

2.8 (1.6–4.2)

3.1 (1.8–4.7)

0.35

  Hs-Troponin (ng/L)

76.5 (34.3–164.8)

88.0 (39.8–162.3)

0.50

  D-dimer (µg/mL)

2.1 (1.1–3.7)

2.5 (1.3–5.0)

0.37

  Ferritin (ng/mL)

667.8 (335.1–1248.5)

714.2 (368.2–1299.0)

0.74

  ESR (mm/h)

67.5 (37.8–97.3)

66.5 (36.3–96.8)

0.84

  CRP (mg/L)

100.0 (46.2–168.5)

120.7 (61.2–194.9)

<0.001

  1. Data presented as N (%) or median (IQR).
  2. For fever, tachypnea, hypoxia and hypotension, Pearson’s two-sided chi-squared test used for hypothesis testing without adjustment for multiple comparisons.
  3. For all other variables, Student’s two-sided t test performed for hypothesis testing without adjustment for multiple comparisons.
  4. ALT alanine transaminase, AST aspartate transaminase, CRP C-reactive protein, ESR erythrocyte sedimentation rate, F Fahrenheit, HR heart rate, IQR interquartile range, IL-6 interleukin 6, SBP systolic blood pressure.
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