Fig. 3: C-terminal receptor–receptor interactions are conserved between human and mouse.
From: Structures of mouse and human GITR–GITRL complexes reveal unique TNF superfamily interactions
Both human (a) and mouse (b) GITR show receptor–receptor interactions (shown in blue, GITRL in orange). Closer examination shows phenylalanine packing at a hydrophobic homodimeric interface in both human and mouse receptors.
