Fig. 4: A conformational change of L104 and H105.

a In NFM bound subunits, Cys76 is close to Leu104 at a distance of 4.9 Å, away from His105 at a distance of 7.7 Å. b In DHP bound subunits, Cys76 is close to His105 at a distance of 4.1 Å, away from Leu104 at a distance of 7.7 Å. Yellow, red, blue, and orange represent carbon, oxygen, nitrogen, and sulfur atoms, respectively.