Fig. 7: Comparison of wild-type and Atoh7-null clusters. | Nature Communications

Fig. 7: Comparison of wild-type and Atoh7-null clusters.

From: Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas

Fig. 7

a Proportions of cells in each wild-type (WT, red) and Atoh7-null (MT, blue) clusters. Nascent retinal ganglion cells (RGCs) (C5) and differentiated RGCs (C6) are highlighted by a red box. Note there is no major change in the proportion of cells in C5, but a marked reduction in C6. Source data are provided. b Scatter plots comparing gene expression in corresponding pairs of WT and MT clusters. The correlation coefficients (R2) are shown for each pair. The C5 and C6 pairs have the lowest R2 values, indicating the most changes in gene expression. c Violin plots showing cluster-specific changes in expression of the Notch pathway genes. Note the distinct expression patterns of individual genes and differential expression changes in the MT clusters (see text for details).

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