Table 1 Enriched GO terms for individual cell states/types.

From: Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas

Term

Count

%

Fold enrichment

P Value

Naive RPCs (C0–C3)

 Cell cycle

64

18.66

5.84

2.63E−30

 Cell division

51

14.87

7.63

2.13E−29

 Mitotic nuclear division

42

12.24

8.49

6.07E−26

 Nucleosome assembly

22

6.41

11.84

1.20E−16

 Chromosome segregation

16

4.66

10.06

4.83E−11

Transitional RPCs (C3, C4)

 RNA splicing

35

10.42

8.42

1.85E−21

 Cell cycle

51

15.18

4.81

2.52E−20

 MRNA processing

37

11.01

6.66

3.06E−19

 Cell division

34

10.12

5.27

1.29E−14

 mRNA splicing, via spliceosome

19

5.65

9.83

7.01E−13

RGCs (C5, C6)

 Nervous system development

63

7.67

4.07

3.24E−21

 Axon guidance

31

3.78

5.07

3.39E−13

 Axonogenesis

25

3.05

5.69

7.00E−12

 Neuron projection development

24

2.92

4.21

1.07E−08

 Substantia nigra development

13

1.58

8.34

2.08E−08

Horizontal an amacrine cells (C7)

 Nervous system development

30

8.17

4.35

7.13E−11

 Axon guidance

16

4.36

5.87

9.73E−08

 Cell differentiation

34

9.26

2.38

6.70E−06

 Neuron migration

12

3.27

5.29

1.71E−05

 Multicellular organism development

38

10.35

2.02

6.55E−05

Photoreceptors (C8, C9)

 Visual perception

25

7.31

4.06

1.39E−08

 Photoreceptor cell maintenance

13

3.80

5.99

1.82E−06

 Synaptic vesicle exocytosis

7

2.05

10.73

4.23E−05

 Negative regulation of transcription from RNA polymerase II promoter

5

1.46

16.13

2.19E−04

 Positive regulation of transcription from RNA polymerase II promoter

26

7.60

2.19

3.79E−04