Table 2 Estimating the association of demographic and behavioral factors with the risk of acquiring and transmitting SARS-CoV-2.
Characteristics | No. of individuals | No. of contacts | No. of contacts per person | No. of secondary infections | Secondary infection attack rate (%, 95%CI) | Data-based OR (95%CI) | Model 1a | Model 2a | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR (95%CI) | P-value | OR (95%CI) | P-value | ||||||||||
Age of infectors | |||||||||||||
0–14 y | 25 | 193 | 7.7 | 2 | 1.0 (0.1, 3.7) | 0.36 (0.04, 1.16) | 0.28 (0.04, 2.04) | 0.210 | – | – | |||
15–64 y | 355 | 6833 | 19.2 | 188 | 2.8 (2.4, 3.2) | Reference | Reference | – | – | – | |||
65+ y | 81 | 1133 | 14.0 | 19 | 1.7 (1.0, 2.6) | 0.61 (0.42, 0.81) | 0.62 (0.25, 1.55) | 0.306 | – | – | |||
Log-transformed age | 461 | 8159 | 17.7 | – | – | – | – | – | 1.57 (0.87, 2.81) | 0.134 | |||
Age of contacts | |||||||||||||
0–14 y | 22 | 936 | 42.5 | – | – | – | 0.58 (0.34, 0.98) | 0.041 | – | – | |||
15–64 y | 154 | 6411 | 41.6 | – | – | – | Reference | – | – | – | |||
65+ y | 33 | 812 | 24.6 | – | – | – | 1.65 (1.03, 2.64) | 0.038 | – | – | |||
Log-transformed age | 209 | 8159 | 39.0 | – | – | – | – | – | 1.26 (1.02, 1.55) | 0.028 | |||
Type of contact | |||||||||||||
Household contacts | – | 1021 | – | 99 | 9.7 (8.0, 11.7) | Reference | Reference | – | Reference | – | |||
Relative contacts | – | 3084 | – | 56 | 1.8 (1.4, 2.4) | 0.19 (0.17, 0.21) | 0.11 (0.07, 0.17) | 2.30e−21 | 0.11 (0.07, 0.18) | 5.37e−21 | |||
Social contacts | – | 2227 | – | 27 | 1.2 (0.8, 1.8) | 0.12 (0.10, 0.15) | 0.06 (0.03, 0.11) | 3.95e−20 | 0.06 (0.03, 0.11) | 1.70e−20 | |||
Other contacts | – | 1827 | – | 27 | 1.5 (1.0, 2.1) | 0.15 (0.12, 0.18) | 0.07 (0.04, 0.13) | 1.73e−18 | 0.07(0.04, 0.13) | 9.75e−19 | |||
Generation of SARS-CoV-2 transmission | |||||||||||||
G1 | – | 2121 | – | 91 | 4.3 (3.5, 5.2) | Reference | Reference | – | Reference | – | |||
G2 | – | 2987 | – | 81 | 2.7 (2.2, 3.4) | 0.63 (0.63, 0.65) | 0.14 (0.06, 0.32) | 3.81e−6 | 0.13 (0.05, 0.29) | 1.25e−6 | |||
G3–4 | – | 965 | – | 19 | 2.0 (1.2, 3.1) | 0.47 (0.34, 0.60) | 0.05 (0.02, 0.19) | 5.04e−6 | 0.05 (0.02, 0.18) | 3.22e−6 | |||
Multiple exposureb | – | 598 | – | 9 | 1.5 (0.7, 2.8) | 0.35 (0.20, 0.54) | 0.11 (0.03, 0.43) | 0.002 | 0.11 (0.03, 0.42) | 0.001 | |||
Unknown | – | 1488 | – | 9 | 0.6 (0.3, 1.1) | 0.14 (0.09, 0.21) | 0.03 (0.01, 0.11) | 8.94e−8 | 0.03 (0.01, 0.11) | 7.45e−8 | |||
Levels of exposure to an infector | |||||||||||||
Total number of contacts | – | 8159 | – | – | – | – | 0.99 (0.97, 1.00) | 0.022 | 0.99 (0.97, 1.00) | 0.030 | |||
Gender of infectors | |||||||||||||
Female | 239 | 4067 | 17.0 | 87 | 2.1 (1.7, 2.6) | Reference | Reference | – | Reference | – | |||
Male | 222 | 4092 | 18.4 | 122 | 3.0 (2.5, 3.5) | 1.43 (1.35, 1.47) | 1.75 (0.96, 3.17) | 0.067 | 1.75 (0.97, 3.18) | 0.064 | |||
Gender of contacts | |||||||||||||
Female | 424 | 4017 | 9.5 | – | – | – | Reference | – | Reference | – | |||
Male | 427 | 4142 | 9.7 | – | – | – | 1.02 (0.74, 1.41) | 0.899 | 1.01 (0.73, 1.39) | 0.964 | |||
Clinical severity of infectors | |||||||||||||
Asymptomatic | 80 | 898 | 11.2 | 15 | 1.7 (0.9, 2.7) | 0.63(0.39, 0.87) | 0.68 (0.25, 1.88) | 0.460 | 0.72 (0.26, 1.98) | 0.523 | |||
Symptomatic | 381 | 7261 | 19.1 | 194 | 2.7 (2.3, 3.1) | Reference | Reference | – | Reference | – | |||
