Fig. 5: T lymphocyte cytokine responses in ART-suppressed tissues.
From: Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques
A, B SIV-Gag specific IFN-γ, IL-2, and TNFα responses in CD69 + CD4 + (A) and CD8 + (B) T cells at necropsy following 1 year of ART for the Late ART monkeys (red dots) and Early ART monkeys (blue dots). Colored dots refer to individual animals. All samples with approximately 2,000 or more CD69 + cells were kept for further analysis. Flow cytometry gating strategy used is illustrated in Supplementary Fig. 7. IFN-γ, Interferon gamma, IL-2, Interleukin 2, TNFα, Tumor necrosis factor alpha.
