Fig. 5: Stage-specific expression of TEs in somatic cell reprogramming. | Nature Communications

Fig. 5: Stage-specific expression of TEs in somatic cell reprogramming.

From: Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE

Fig. 5

a Trajectory reconstruction during OKSM reprogramming, cells are colored by time point. b As in (a), but cells are colored by the expression of the indicated TEs. c Force-directed (FR) layout of cells during OKS reprogramming, cells are colored by time point. d Same with (c), but cells are colored by the expression change of the ERVB7_1-LTR_MM TE during reprogramming. e Expression heatmap of the top 145 dynamically expressed TEs in a pseudotime ordering for the RP branch, selected TEs are indicated. f Expression changes of the indicated TEs during reprogramming. g Trajectory reconstruction during chemical reprogramming, cells are colored by time point. h As in (g), but showing TE expression specific to the successful or failed branches of reprogramming.

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