Fig. 6: HAT as a point of care test.
From: A haemagglutination test for rapid detection of antibodies to SARS-CoV-2
Capillary blood samples were obtained by Lancet. Antibodies to the RBD were detected by HAT on autologous red cells in the sample in “Test” wells (plasma at 1:40) after addition of 100 ng/well IH4-RBD (see “Methods”). NC negative control (PBS replaces IH4-RBD), PC positive control (20 ng/well CR3022, an anti-RBD monoclonal antibody added). In parallel, after removal of red cells, the plasma was tested in a standard ELISA for detection of antibodies to the RBD. Low levels of antibody detected in the ELISA were sufficient to give a positive result in the HAT. Detection of antibodies by HAT on autologous red cells obtained by finger prick has been repeated multiple times in both Oxford and Toulouse, and will be the subject of a future report. Source data are provided as a Source Data file.
