Fig. 4: Target gene prediction of regulatory elements. | Nature Communications

Fig. 4: Target gene prediction of regulatory elements.

From: Functional annotations of three domestic animal genomes provide vital resources for comparative and agricultural research

Fig. 4

a Topologically associated domains (TADs) predicted by CTCF ChIP-seq data. b The number of predicted RE–gene pairs, the total number of REs and genes in at least one pair, and the mean and median number of predicted genes per RE and REs per gene. c Spearman rank correlation of normalized read depth in each genic RE with the expression of the gene it overlaps (blue bars) and the expression of the genes predicted as targets (orange bars). d Spearman rank correlation of normalized read depth in each intergenic RE with the expression of the nearest gene (blue bars) and the expression of the genes predicted as targets (orange bars). e Principal component plot of the normalized read depth of H3K27ac of intergenic REs predicted to target genes with one-to-one orthologs across all three species.

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