Fig. 7: Recombinant BMPER protein improves glucose responses in DIO mice.
From: Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance

C57BL/6 mice were fed HFD or control chow (CC) for 4 weeks and then injected with recombinant BMPER protein at 0.1 mg/kg/mouse every other day for 6 weeks. Metabolic parameters were measured, including a Body weight. b Fasted insulin. c Fasted glucose. d Glucose tolerance tests. e Insulin tolerance tests. n = 4 mice (a CC), 5 mice (a HFD), and 5 mice (b–e). Data are presented as mean values ± SEM. NS not significant. Analysis was one-way ANOVA (for a–c) or two-way ANOVA (for d, e) followed by Fisher’s LSD multiple comparison test.