Fig. 2: Identification of IEL CD8+ T cell and CD4+ T cell subsets by flow cytometry. | Nature Communications

Fig. 2: Identification of IEL CD8+ T cell and CD4+ T cell subsets by flow cytometry.

From: Single-cell analyses of Crohn’s disease tissues reveal intestinal intraepithelial T cells heterogeneity and altered subset distributions

Fig. 2

a Schematic t-SNE clustering of IEL CD8+ T cells. Number illustrates the relationship with clusters observed by scRNA-seq. Asterisk illustrates the different experimental approach. U; undefined. b t-SNE clustering of IEL CD8+ T cells from a representative donor showing expression of CD103, CD39, and KLRG1. c Schematic t-SNE clustering of IEL CD4+ T cells. Number illustrates the relationship with clusters observed by scRNA-seq. Asterisk illustrates the different experimental approach. d t-SNE clustering of IEL CD4+ T cells from three representative donors showing expression of CD161, CD39, GP130, TIGIT, BTLA, PD-1, ICOS, and CD25.

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