Fig. 2: Identification of a 6-TG biosynthetic gene cluster in S. chromogenes. | Nature Communications

Fig. 2: Identification of a 6-TG biosynthetic gene cluster in S. chromogenes.

From: Coagulase-negative staphylococci release a purine analog that inhibits Staphylococcus aureus virulence

Fig. 2

a Molecular structure of 6-thioguanine. b E. amylovora ycf operon and S. chromogenes 6-TG biosynthetic operon. c Simultaneous antagonism assay using RN4220 pEmpty and ptgs on TSA. d S. aureus was cultured in TSB containing supernatant from RN4220 pEmpty or ptgs and plated 24 h.p.i and CFU/mL were enumerated. Results are pooled from two independent experiments, each with n = 3 replicates per condition. Data are shown as mean ± SD (**p ≤ 0.01. Two-sided unpaired t-test).

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