Fig. 4: Protonation and active site coordination of MnSOD.
From: Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase
a, b Neutron structures of five-coordinate Mn3+SOD and Mn2+SOD. Green omit |Fo|−|Fc| difference neutron scattering length density is at 3.0σ. c The six-coordinate Mn2+SOD active site of Chain A with green omit |Fo|−|Fc| difference density displayed at 2.0σ, 2.5σ, and 3.0σ for blue, green, and orange contours, respectively. |Fo|−|Fc| difference density is for individual D atoms except for the upper-right corner that is for both atoms of the anionic oxygen ligand (OL). Light blue 2|Fo|−|Fc| neutron scattering length density is displayed at 1.0σ. Numbers are distances in Å. For the oxidized state, only one chain is shown due to high structural similarities, see Supplementary Fig. 2 for chain B.
