Fig. 1: Patient and sample flow in the study.
From: Microbiota-based markers predictive of development of Clostridioides difficile infection
The flow chart provides an overview of participating patients in each processing step, number of samples collected at each timepoint, and reasons for sample exclusion or non-collection. D1: rectal swab sample collected upon study enrollment. D6: rectal swab collected ~6 days after initiation and at the end of antibiotic treatment. S1: stool sample collected at the first occurrence of diarrhea (variable time-point). AAD: patients with non-C. difficile antibiotic-associated diarrhea. CDI: patients with confirmed C. difficile infection. ND: non-diarrheic patients. PBL: penicillin + beta-lactamase inhibitor. OBL: other beta-lactamase antibiotics. FQN: fluoroquinolones.
