Fig. 2: Association of lead cholesterol-lowering chrXq23 variant rs5942634-T with reduced odds of coronary heart disease and diabetes mellitus type 2.

The lead cholesterol-lowering allele at chrXq23 (i.e., rs5942634-T) and evidence of association with coronary heart disease and diabetes mellitus type 2 in each of three datasets in black, UK Biobank, HUNT, and FinnGEN, as well as meta-analysis in blue are shown. Odds ratios (OR) and 95% confidence intervals around the odds ratios are displayed.