Fig. 3: Colocalization of expression of genes at chrXq23 in subcutaneous adipose tissue with blood cholesterol effects strongly implicates CHRDL1. | Nature Communications

Fig. 3: Colocalization of expression of genes at chrXq23 in subcutaneous adipose tissue with blood cholesterol effects strongly implicates CHRDL1.

From: Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Fig. 3

The x-axis represents eight genes in the chrXq23 locus and y-axis represents standardized gene expression effect estimates in subcutaneous adipose tissues with 95% confidence intervals. Accounting for linkage disequilibrium, standardized effects and evidence of associations of cholesterol-lowering alleles were correlated with gene expression of genes at chrXq23 (ACSL4, TMEM164, AMMECR1, RTL9, CHRDL1, PAK3, CAPN6, and DCX).

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