Fig. 4: Structural comparison of four FAS-type enzymes.

a Ribbon representation of the E. coli FabB structure (PDB: 1G5X). b Ribbon structure of the E. coli FabF (PDB: 2GFW). c Ribbon representation of the E. coli FabH structure (PDB: 1HN9). d Ribbon illustration of the A. tumefaciens BioZ structure (PDB: 6KUE). The lid domains in EcFabB (a), EcFabF (b), and EcFabH (c) are separately colored in green, cyan, and yellow, respectively. Whereas, the core domains are colored in silver–gray. As for AtBioZ, the lid domain is shown in red, and its core domain appears in blue (d). The three catalytic triad residues are indicated with pink letters.