Fig. 1: Phylogenetic analysis of AA7-like sequences. | Nature Communications

Fig. 1: Phylogenetic analysis of AA7-like sequences.

From: Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs

Fig. 1

a The phylogenetic tree is based on 1927 sequences. Biochemically characterized enzymes are coloured according to clade, with green circles indicating enzymes from the present study. The PDB entries (in square brackets) are given for available enzyme structures. Clade Va harbours the canonical previously described oligosaccharide oxidases: SsGOOX15 from Sarocladium strictum active on cellooligosaccharides, MnLaO16 from Microdochium nivale active on lactose, TtXylO17 from Thermothelomyces thermophilus active on xylooligosaccharides and FgChitO18 from Fusarium graminearum active on chitooligosaccharides. Clade I contains characterised plant enzymes33,39 that are not assigned in AA7 including the oligogalacturonide oxidase (AtOGOX1)13 from Arabidopsis thaliana13,33,39. b Clade-wise taxonomic distribution of putative AA7 sequences. c Clade-wise conservation percentage of the histidine and cysteine FAD-cofactor tethering residues. The number of sequences within each clade is indicated above each bar. The accessions of the sequences in the tree are provided in the Source Data file.

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