Fig. 4: Synthetic utility.

a Diverse synthesis of cis-polysubstituted chiral piperidines 12. b Synthesis of chiral tetrahydropyridine 14. c Diels-Alder reaction to bridged rings 15. †Using Pd/C instead of PtO2·H2O.
a Diverse synthesis of cis-polysubstituted chiral piperidines 12. b Synthesis of chiral tetrahydropyridine 14. c Diels-Alder reaction to bridged rings 15. †Using Pd/C instead of PtO2·H2O.